Walsh JJ, Llorach P, Cardozo Pinto DF, Wenderski W, Christoffel DJ, Salgodo JS, Heifets BD, Crabtree GR, Malenka RC. Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD. Neuropsychopharmacology. 2021 Jul. doi: 10.1038/s41386-021-01091-6. PMID: 34239048


Christoffel DJ*, Walsh JJ*, Hoerbelt P*, Heifets BD, Llorach P, Lopez RC, Ramakrishnan C, Deisseroth K, Malenka RC. Selective filtering of excitatory inputs to nucleus accumbens by dopamine and serotonin. Proceedings of the National Academy of Sciences. 2021 Jun; 118(24):e2106648118. doi: 10.1073/pnas.2106648118.PMID: 34103400

Christoffel DJ, Walsh JJ, Heifets BD, Hoerbelt P, Neuner S, Sun G, Ravikumar VK, Wu H, Halpern CH, Malenka RC. Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding. Nature Communications. 2021 Apr; 12(1):2135. doi: 10.1038/s41467-021-22430-7. PMID: 33837200

Wenderski W, Wang L*, Krokhotin A*, Walsh JJ, Li H, Shoji H, Ghosh S, George RD, Miller E, Elias L, Gillespie MA, Son EY, Staahl BT, Baek ST, Stanley V, Moncada C, Shipony Z, Linker SB, Marchetto MC, Gage FH, Chen D, Sultan T, Zaki MS, Ranish JA, Miyakawa T, Luo L, Malenka RC, Crabtree GR, Gleeson J. Loss of neural-specific BAF subunit ACTL6B relieves repression 5 of early response genes and causes recessive autism.  Proceedings of the National Academy of Sciences. 2020 May; 117(18):10055-10066. doi: 10.1073/pnas.1908238117. Epub 2020 Apr. PMID: 32312822

Heifets BD, Salgado JS, Taylor MD, Hoerbelt P, Cardozo Pinto DF, Steinberg EE, Walsh JJ, Sze JY, Malenka RC. Distinct neural mechanisms for the prosocial and rewarding properties of MDMA. Science Translational Medicine. 2019 Dec; 11(522):eaaw6435. doi: 10.1126/scitranslmed.aaw6435. PMID: 31826983

Walsh JJ, Christoffel DJ, Ben-Dor GA, Selimbeyoglu A, Hung LW, Deisseroth K, Malenka RC. 5-HT release in nucleus accumbens rescues social deficits in mouse autism model. Nature. 2018 Aug; 560(7720):589-594. doi: 10.1038/s41586-018-0416-4. PMID: 30089910

Juarez B, Morel C, Ku SM, Liu Y, Zhang H, Montgomery S, Gregoire H, Ribeiro E, Crumiller M, Roman-Ortiz C, Walsh JJ, Jackson K, Croote DE, Zhu Y, Zhang S, Vendruscolo LF, Edwards S, Roberts A, Hodes GE, Lu Y, Calipari ES, Chaudhury D, Friedman AK, Han MH. Midbrain circuit regulation of individual alcohol drinking behaviors in mice. Nature Communications. 2017 Dec; 9(1):2220. doi: 10.1038/s41467-017-02365-8.PMID: 29263389

Hung LW, Neuner S, Polepalli JS, Beier KT, Wright M, Walsh JJ, Lewis EM, Luo L, Deisseroth K, Dolen G, Malenka RC. Gating of social reward by oxytocin in the ventral tegmental area. Science. 2017 Sep; 357(6358):1406-1411. doi: 10.1126/science.aan4994. Epub 2017 Sep. PMID: 28963257

Previous publications can be found here.

Reviews

Walsh JJ, Christoffel DJ, Malenka RC. Neural circuits regulating prosocial behaviorsNeuropsychopharmacology. 2022 Jun; doi:10.1038/s41386-022-01348-8. PMID: 35701550

 

Walsh JJ, Christoffel DJ, Wu X, Pomrenze MB, Malenka RC. Dissecting neural mechanisms of prosocial behaviors. Current Opinion in Neurobiology. 2021 Jun; 68:9-14. doi: 10.1016/j.conb.2020.11.006. PMID: 33278639

Walsh JJ, Han MH. The heterogeneity of ventral tegmental area neurons: projection function in a mood-related context. Neuroscience. 2014 Dec; 282:101-8. doi: 10.1016/j.neuroscience.2014.06.006. PMID: 24931766